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Deluxe Double
$656 for 3 nights Rate details
Cancel or change by June 27, 2026.
$656 for 3 nights Rate details
Cancel or change by June 27, 2026.
$656 for 3 nights Rate details
Cancel or change by June 27, 2026.
Luxury King
$785 for 3 nights Rate details
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Luxury Double
$785 for 3 nights Rate details
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Asleep in the Cyclone
$1,396 for 3 nights Rate details
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Atrium Suite
$2,137 for 3 nights Rate details
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Corner Suite
$2,137 for 3 nights Rate details
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Please note: room photos and descriptions are representative of the room category. Actual rooms may vary from what is shown. Information and pricing is subject to change without notice. While we do our very best to ensure that information appearing in this website is complete and accurate, we cannot be responsible for incomplete and inaccurate representations, which may or may not be under our control. Rates are quoted in USD, based on double occupancy, and are per room, per night, and include any free nights or other discounts, unless otherwise specified. Additional guests in the room, children, roll-away beds, and incidental charges may be at an additional cost.
21c Louisville is the first of its kind: boutique hotel, chef-driven restaurant, and 21st century art museum all under one roof. 21c is located in the heart of downtown Louisville, on historic Museum Row neighboring cultural destinations like the Kentucky Museum of Art and Craft, the Louisville Slugger Museum, and the Muhammad Ali Center. And just a short walk or drive the KFC Yum Center Arena, Louisville Palace Theatre, Louisville Waterfront Park, a host of food and beverage destinations, and of course, all the bourbon you dream of. Enjoy a peaceful stay in modern luxury when you SLEEP WITH ART.
21c Museum Hotel Louisville
700 W Main St
Louisville, Kentucky
40202
Nearest Airport: SDF
We stayed here to do some bourbon trail exploration. The location ended up being a little far from the activities we were interested in, but close to the Louisville Slugger and Mohammad Ali museums which was good for a rainy day. The room was comfortable. Walls are paper thin and AC is loud, so earplugs recommended. Rooms are very dark, despite having a window. Overall it was clean and comfortable. Staff seemed to lack some attention to detail, but all were pleasant enough. I’m not sure I would bring any younger (minor) travelers here as several pieces of artwork seemed to be overly sexual in the dining area. Food left a lot to be desired at breakfast and dinner. Breakfast staff were exceptionally friendly and helpful.
Arstrazz - Lakeland, Florida
I booked a stay at 21c as part of a small bachelorette weekend and, unfortunately, the experience fell far short of what I expected from a “boutique luxury” hotel and spa experience. The biggest disappointment was the spa experience. This was a staycation to celebrate my sisters upcoming wedding, and was a rare treat for my mom, my two sisters, and me. We booked massages approximately a month in advance specifically to enjoy them together as part of the celebration, only to have three of the appointments canceled the morning of. While I understand staffing issues and unforeseen circumstances can happen, what was most surprising was the lack of communication, apology, or any meaningful effort to recover the experience. Even after politely inquiring whether there might be any accommodation or consolation offered due to the last-minute change, there was essentially no acknowledgment of the inconvenience. Additionally, communication surrounding the spa logistics was confusing from the start. There is no dedicated spa reception area, and all coordination goes through the hotel front desk, which created uncertainty about where to report for appointments. The steam room was also out of order, eliminating one of the few amenities we had planned to enjoy together. The spa itself was also extremely underwhelming compared to expectations. Rather than feeling private or luxurious, the space felt more comparable to a basic gym locker room adjacent to the fitness center — tiled floors, dim lighting, and very little sense of atmosphere or relaxation. The massage room itself was similarly sparse and lacked the elevated feel typically associated with boutique hotel spas. To make matters more uncomfortable, my sister was told by the massage therapist that her “other appointment canceled,” which was simply untrue, as the spa had canceled on us earlier that day. There was also confusion regarding gratuity. When booking, I was informed that the included 20% service fee covered the therapist gratuity. However, after the massage, the therapist stated that the fee was not her tip, leading my sister to leave an additional gratuity that was then charged to my card. Clearer communication on this policy would be appreciated. After checkout, I also had to follow up three separate times to obtain my receipt, and the only receipt ultimately provided reflected valet parking charges rather than the full stay and spa services. The hotel room itself was acceptable, though underwhelming. Our room had a very small window facing a concrete vestibule with almost no natural light. While I understand room assignments are partially luck of the draw, I had noted in advance that this was a celebratory stay and had hoped for a slightly more thoughtful accommodation. To be fair, the one aspect of service that was handled well was early check-in, which the hotel graciously accommodated free of charge and which I appreciated. Overall, I left feeling disappointed not because of one isolated issue, but because the experience consistently failed to meet the level of service, communication, and atmosphere that 21c markets itself as providing. I want to add that I also reached out to hotel management directly following our stay to provide this feedback and did not receive a response, which was disappointing.
Shelby W
The lack of light in the room is a problem. It is very dark. We have stayed at 21C many times but this time the front desk staff were too busy to say good morning or anything at all. It was not a friendly vibe.
sadeba - Chicago, Illinois
A lovely hotel in a great location. A major downside is that the rooms have little noise protection. I was in room 421. I heard Every Word the occupants of room 422 spoke for the length of my stay. When I checked out, the staff at the front desk suggested they were aware of this issue. Buyer beware.
rdclark55 - Cleveland, Ohio
My overall experience here was excellent. The staff, beginning with the Valet that opened our doors and greeted us upon arrival, to the front desk team to the restaurant staff and the housekeeping staff were all inviting, friendly and professional. The room was spacious and clean. The museum setting was nice and the downtown location was perfect. A highlight was the migrating red penguins. It was quite the game to see where they’d end up every day. The downside? The restaurant had a limited menu so we only ate two meals there, 1 breakfast and 1 dinner. The website mentioned a pool, there is not one. That said, I would definitely stay here again and again.
Rick R - Omaha, Nebraska
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