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We recommend booking a stay with free cancellation in case your plans change. Accessible rooms
ADA Accessible, Deluxe Two Queen Accessible
USD $ 172 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
ADA Accessible, Deluxe King Accessible Roll-in Shower
USD $ 172 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Deluxe King
USD $ 172 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Deluxe Two Queen
USD $ 172 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Deluxe Two Double
USD $ 172 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
ADA Accessible, Deluxe King Accessible
USD $ 172 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Studio Suite
USD $ 218 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Deluxe Queen Suite
USD $ 232 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Luxury King Suite
USD $ 252 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
ADA Accessible, Luxury Suite Accessible Roll-in Shower
USD $ 252 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Corner Suite
USD $ 272 /nt
You have until August 8, 2025 to cancel this reservation without penalty.
Please note, room photos and descriptions are representative of the room category. Actual rooms may vary from what is shown. Upgrades, early check-in, and late check-out are based on availability.
Expect the unexpected in the Windy City. Located just steps from the famous Magnificent Mile, Millennium Park, and renowned museums in downtown Chicago, contemporary art surrounds and inspires you at 21c Museum Hotel Chicago. Discover a new kind of cultural and travel experience with this multi-venue museum and 297 room boutique hotel featuring 106 suites. Stay with us and the iconic Evergreen Penguin.
21c Museum Hotel Chicago
55 E Ontario St
Chicago, Illinois
60611
Nearest Airport: ORD
Jervonte was very helpful with finding the perfect room for us. He was very excited to show us around. Really appreciate your help.
Eni A
Very artsy lobby and convenient location in the heart of Chicago. We had a good time at this location. There wasn’t much for concierge or valet services to check in or they were busy was one of my only issues. The view is nothing to really enjoy as we just faced the abutting buildings and roofs.
Scott C - Panama City, Panama
Came in very late due to travel delays. We were so tired and had such a tough day. The woman at the front desk offered us her own personal soda that she had brought and was extremely kind to us. Made our night with a small, kind gesture!
Courtney P
Amazing! Perhaps the most unique hotel visit you will encounter anywhere. It literally combines a high-end hotel venue with a first- class art museum, from the entry lobby exhibit spaces and compact film viewing theater to its full second-floor galleries. The guest rooms are creatively laid out as comfortable suites; with luxury appurtenances. It has all the other amenities one would expect from a first- class hotel, including a spa and extensive fitness center. Plus, the hotel restaurant and bar are artfully designed and the menu items are well-prepared and impressively presented. Located just off of North Michigan Avenue's attractions, the 21c Museum Hotel is, itself, a destination. We highly commend it for your Chicago visit. Larry and Jean Murphy Evanston, Il
Larry M
Pleasant stay and friendly staff especially Emmanuelle and Alyssa. Thanks guys. We applied our Amex benefits which was nice. Smooth checkin. The art was nice. Really appreciate Erick who went above and beyond to accommodate us for our buisness needs which made the whole experience worthwhile.
J L
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